Dr Sabine Hazan

Ventura Clinical trials (VCC) is at the forefront of drug development. Founded by Leading experts in Gastroenterology and Cardiology. It is a physician owned company with over 22  years of experience in clinical trials.

VCC brings together board certified physicians, Ventura patients from our large database, regulatory personnel , nurses, pharmacists, psychologists, nutritionist, highly experienced clinical research coordinators and highly specialized support technicians. Based in Ventura but with offices in Westlake and Malibu, our facilities have state of the art equipment.

We conduct phase I to IV studies and have access to private endoscopy centers, cardiac centers, pathology centers as well as radiology. We are also affiliated with 2 community hospitals and provide a 48 hours turn around for IRB approval as well as trial and budget approval.

Our regulatory team as well as our recruiting team has been amongst the first in previous studies in study start – up and finishing time.

Our Quality assurance department and performance allows you to make great decisions about your product.

 Enroll now——>Ulcerative colitis 


Ulcerative colitis is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive system where water is removed from undigested material, and the remaining waste material is stored. The rectum is the end of the colon adjacent to the anus. In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms of abdominal pain, diarrhea, and rectal bleeding.

Ulcerative colitis is closely related to another condition of inflammation of the intestines called Crohn’s disease. Together, they are frequently referred to as inflammatory bowel disease (IBD). Ulcerative colitis and Crohn’s diseases are chronic conditions. Grohn’s disease can affect any portion of the gastrointestinal tract, including all layers of the bowel wall. It may not be limited to the GI tract (affecting the liver, skin, eyes, and joints). UC only affects the lining of the colon (large bowel). Men and women are affected equally. They most commonly begin during adolescence and early adulthood, but they also can begin during childhood and later in life.

To find out if you qualify for this study and compensation  please fill out form and call 800) 905-4112

Vitamin D and Excessive Urination

Vitamin D and Excessive Urination

| By Betty Holt

Vitamin D and Excessive Urination
Toilet Photo Credit kostsov/iStock/Getty Images

Vitamin D, sometimes known as the “sunshine vitamin,” plays an important role in many of the body’s functions, and a deficiency in it can cause some serious problems. However, taking excessive amounts of vitamin D can also be troublesome. Vitamin D is a fat-soluble vitamin that is not excreted in the urine if you consume too much. Certain medications might raise vitamin D levels in the bloodstream, while others might decrease it. Check with your doctor before supplementing vitamin D.

Vitamin D

Vitamin D is stored by the body and is activated when your skin meets sunlight. It is also found in some foods, most notably milk that has been fortified with the vitamin. Two forms of vitamin D exist — ergocalciferol, or vitamin D2, and cholecalciferol, or D3. The latter is considered to be better at raising blood levels of the vitamin. Proper amounts of vitamin D can prevent osteoporosis, rickets and osteomalacia because it helps the body absorb and use calcium. It also might help prevent high blood pressure; balance problems; certain cancers such as colon, breast, prostate, skin and pancreatic; seasonal affective disorder; diabetes; multiple sclerosis; obesity; and overall mortality. New guidelines from the Institute of Medicine in November 2010 recommend that adults up to age 70 get 600 international units of vitamin D daily. Over age 71, they should get 800 IUs.

Excessive Urination

Frequent urination means needing to urinate more often than usual, as opposed to urgent urination, which is a sudden, compelling urge to urinate accompanied by bladder discomfort. Frequent urination at night is called nocturia. Most people can go for six to eight hours at night without having to urinate. High doses of vitamin D, in excess of 1,000 IUs per day, can cause frequent urination, according to the website Spine Universe. The National Institutes of Health has set the maximum upper limit at 1,000 IUs for children under age 12 and 2,000 IUs for adults, but some researchers argue these limits are too low. Consult with your doctor if you are taking more than 1,000 IUs per day and experiencing excessive urination.

Other Side Effects

Calcitriol is a form of vitamin D prescribed to treat bone disorders and low levels of calcium in the blood caused by disorders of the kidneys or parathyroid glands. Side effects of this form of vitamin D include increased urination, excessive thirst, metallic taste in the mouth, weight loss, poor appetite, tiredness, sore eyes, itchy skin, vomiting or diarrhea, constipation and problems with muscles, according to MedlinePlus. If you are experiencing any of these side effects, you might need to see your doctor and cut back on your dosage.

Other Causes of Frequent Urination

Frequent urination could also be caused by diabetes, pregnancy or prostate problems. Additionally, the following also can be causes of frequent urination: anxiety, interstitial cystitis, diuretic medicines, overactive bladder syndrome, prostatitis or enlarged prostate, stroke or other brain or nervous system diseases, a tumor or mass in the pelvis, urinary incontinence and vaginitis. Less common causes include radiation therapy to the pelvis, bladder dysfunction or bladder cancer. Drinking too much liquid before bedtime, especially those high in caffeine or alcohol, can cause frequent urination at night.


Dr Sabine Hazan-Steinberg


Ventura clinical trials

 Dr. Sabine Hazan-Steinberg

  • Founder/CEO Ventura Clinical Trials
  • Founder/CEO Malibu Speciality Center
  • Gastroenterology/
  • Hepatology/Internal Medicine
  • Past Chief of Medicine at Community Memorial Hospital
  • Active Consultant for CRG
  • Active Speaker for Pharmaceutical companies
  • 22 Years Experience in Clinical Trials

    About Dr. Sabine Hazan

    Dr. Sabine Hazan has over 22 years of experience in clinical trials and is the Founder and CEO at both Ventura Clinical Trials and Malibu Specialty Center.  As Principal Investigator, Dr. Hazan personally oversees clinical trials for high profile studies on diseases such as Hepatitis C, Hypercholesterolemia, and Pancreatic Cancer.  Her companies are leaders in Cardiovascular studies, Endocrine disorders, Infectious Diseases, Skin disorders and Gastrointestinal diseases and employ cutting edge technology and research practices to provide the best quality in drug therapy research.

    The first woman ever accepted into the University of Florida as a Clinical Gastroenterology Fellow, Dr. Sabine Hazan is a pioneer in the medical field.   Board certified in Gastroenterology, Hepatology, and Internal Medicine, Dr. Hazan has published articles in numerous prestigious medical journals, including theJournal of Duval County Medical Association and Gastroenterology, and won several awards, such as the Best Fellow Scientific Presentation and Dean’s Research Award awarded by University of Florida.  In addition,  Dr. Sabine Hazan is an acclaimed speaker and presented symposiums for influential medical organizations like the American 
Society for Gastrointestinal Endoscopy and Astra Merk, Inc.

    Dr. Sabine Hazan is the former Chief of Medicine at Community Memorial Hospital and an active consultant for CRG.  She currently retains medical licenses in three states (California, Florida, and New York).

    Personal Philosophy

    “I use logic when practicing and try to think outside the box. I always remind myself that much like every fingerprint is different, every patient’s symptom is different and one cannot practice like a robot. We are all humans attempting to stay a little bit longer on the planet. I never assume anything and never take anything lightly. I always try to be patient and listen and play detective with all the clues. Mostly, I realize that I am just a messenger and observe the miracles of healing that come from a higher power.

    Every action leads to a reaction is pure scientific thinking but the reason behind the action is unknown. We, humans are only specks on this planet who must recognize the presence of a higher power. As hard as existence is for everyone, it is just that “an existence for a fraction of time” and as much as we come to doctors for answers we must realize that sometimes there are no answers or reason.”

    Educational Background

    1987 – 1992 DALHOUSIE UNIVERSITY, Nova Scotia, Canada

    MEDICAL DIPLOMA (M.D) Awarded May 1992

    1984 – 1987 CONCORDIA UNIVERSITY, Montreal, Canada

    Bachelor of Sciences (BSc.) Biology Major, Physical Therapy and Minor Nutrition

    1982 – 1984 CEGEP BREBEUF, Montreal, Canada

    D.E.C. Specialty in Health, Pure & Applied Sciences

    1) Be R, Hazan S, Gretz J, Buckley E, Kolts BE, McGee JB, Castell DO and SR Achem.Lower Esophageal Sphincter Relaxation time: Normal values and prevalence of abnormal values in Patients with Noncardiac Chest pain and /or dysphagia. Journal of Duval County Medical 
Association. – 47;7;296. June 1996.

    2) Hazan S, Buckley F, Castell DO and Achem SR. Octreotide Improves Sensory and Pain Thresholds in Patients with Noncardiac Chest Pain. Journal of the Duval County Medical Association. 47;7;291. June 1996.

    3) Be R, Hazan S, Gretz J, Buckley E, Kolts BE, McGee JB, CasteLl DO an SR Achem. Lower Esophageal Sphincter Relaxation time: normal values and prevalence of abnormal values in Patients with Noncardiac Chest pain and/or Dysphagia. Gastroenterology. April 1996;110:A6

    To find out if you qualify for our current clinical trials and  compensation please fill out form and call 800) 905-4112